Destination Startup
Investor Registration Now Open—Request Invitation
A collaboration among leading research universities and federal laboratories across the Intermountain Westtoshowcasethe best companiesfrom ourinnovation ecosystem.
Launched in 2018, Destination Startup® connects investors with groundbreaking startups built on novel discoveries from leading national labs and universities in the Intermountain West. Designed for deal-flow, the showcase is for active investors, who can request an invitation here. Participating startups must be actively raising and are selected through a competitive review process and robust pitch preparation. With over $1.2 billion collectively raised to date by startups likeVitriVax,Arpeggio Biosciences ԻManifest Technologies, Destination Startup is for investors and founders ready to catalyze real-world impact.
Startups come from these participating institutions
Arizona State Թ, Colorado School of Mines, Colorado State Թ, Montana State Թ, National Institute of Standards and Technology (NIST), National Laboratory of the Rockies (NLR), Texas Tech Թ System, Թ Corporation for Atmospheric Research (UCAR), Թ of Arizona, Թ of Colorado (Boulder, Anschutz, Denver and Colorado Springs), Թ of Denver, Թ of Kansas, Թ of Nebraska-UMC, Թ of New Mexico, Թ of Utah, Թ of South Dakota and Թ of Wyoming.
The Destination Startup Impact
$1.2B+
Collective venture, angel, strategic and grant funding raised to date by presenting startups
1000+
Investors, business leaders and innovators from across the continent who attended
128
Companies that have presented
Investors: Attend the Investor Showcase
The Destination Startup Investor Showcase is an invite-only showcase of new companies actively raising funds to commercialize groundbreaking bio- and physical science inventions from leading research institutions across the Intermountain West. It demonstrates a powerful way to invest in advancing innovative research and translate it into impactful business ventures. Designed for deal-flow, the showcase is for active investors, who can request an invitation to attend. Interested investors are encouraged to request an invitation as soon as possible, as seating is limited.
Destination Startup Investor Showcase
Thursday, Feb. 26, 2026, 8 a.m.-6 p.m., Boulder, CO
Investor registration closes Wednesday, Feb. 19
Presenting Startups
⚠ These company names and descriptions reflect their status at the time of their Destination Startup presentations and may not represent their current state.
2026 Presenting Startups
EsterCycle breaks down mixed petroleum and bio-based polyester plastics to enable the transition to renewable and circular materials. At commercial scale, plastics recycled by EsterCycle will be economically competitive with and indistinguishable from virgin materials while reducing emissions by 46%.
Team:Julia Curley, Founder, CEO; , CCO
Affiliation: National Laboratory of the Rockies (NLR)
Funding Round: Pre-Seed
Industry Applications: Environment and Sustainability, Cleantech, Manufacturing, Chemicals
We are developing epigenetic therapies to modulate undruggable immune pathways. Our lead program uses mRNA-delivered epigenetic repressors to silence MYD88, a central driver of hyperinflammation previously considered beyond reach. This approach enables the first targeted treatment for HLH, a fatal orphan disease.
Team:, Co-Founder, CEO; , Co-Founder, CTO; , Scientific Co-Founder
Affiliation: Arizona State Թ
Funding Round: Seed
Industry Applications: Biotech, Therapeutics
At Green Steel Environmental, we are redefining how an industry thinks about environmental stewardship. Our mission is to eliminate hazardous chemicals from wastewater treatment and replace them with clean, upcycled materials that protect our water ecosystem. Join us as we build a circular economy in nutrient recovery.
Team:, Co-Founder, CEO; , Co-Founder, COO; Mark Hernandez, Co-Founder, CSO; , CRO; , Environmental Engineer
Affiliation: Թ of Colorado Boulder
Funding Round: Series A
Industry Applications: Advanced Materials, Environment and Sustainability, Cleantech, Food and Agriculture, Chemicals
Kioga is a biotech company developing clinically validated neuromodulating postbiotics based on beneficial microbes in nature, essential for immune and mental resilience that are missing from modern life. Kioga is building a new ingredient category at the intersection of immunology, neuroscience and wellness.
Team: Justin Whiteley, Co-Founder, CEO; Adam Bohr, Co-Founder, Head of Business Operations; Chris Stamper, Co-Founder, Head of R&D; Chris Lowry, Co-Founder, Scientific Advisor; Noah Fierer, Co-Founder, Scientific Advisor
Affiliation: Թ of Colorado Boulder
Funding Round: Seed
Industry Applications: Food and Agriculture, Health and Wellness, Biotech
Kitsune Bio develops shape-shifting cyclic peptides that penetrate cells to hit intracellular protein targets. Our ML platform accelerates permeability optimization for internal programs and helps partners rescue stalled peptide assets.
Team:, Co-Founder, CEO; , Co-Founder, CEO; Michael Stowell, Co-Founder, CSO; Thomas Fallon, Co-Founder, Scientific Advisor
Affiliation: Թ of Colorado Boulder
Funding Round: Pre-Seed
Industry Applications: Biotech, Therapeutics
LIDG3D develops a powderless metal 3D printing technology that uses light to directly form metal parts from metal salts derived from raw minerals or recycled electronic waste. By eliminating metal powders and molds, the process reduces cost, energy use and waste.
Team:, Founder, CTO; , CEO
Affiliation: Arizona State Թ
Funding Round: Pre-Seed
Industry Applications: Additive Manufacturing
TrialWear by Loop Clinical Systems is a wearable and analytics platform integrating real-time patient signals, self-reported experiences and geospatial data to improve safety monitoring, adverse event detection and equitable access in decentralized and rural clinical trials.
Team:, Founder, CEO; Brianna Daniels, Community Engagement; Noah Hedding, Electrical Engineering; Lea Molnar, Mechanical Engineering; Jiahui Ma, Data Science
Affiliation: Montana State Թ
Funding Round: Pre-Seed
Industry Applications: Health and Wellness, Information Technology
Manifest Technologies is building the next generation of manufacturing. Its Parallax Volumetric Additive Manufacturing uses precision light to form fully solid parts instantly delivering 10 to 100x faster production and unlocking true design freedom for factory-scale manufacturing in optics and medical devices.
Team:, Co-Founder, CEO; , Co-Founder, CTO; , Chief Scientist; , Product Engineer; , Materials Engineer; , Senior Optical Scientist; , Director of Software Innovation; , Product Manager
Affiliation: Թ of Colorado Boulder
Funding Round: Seed
Industry Applications: Advanced Materials, Hardware and Instrumentation, Robotics, Manufacturing
Modendo develops ultra-thin fiber endoscopes—probes as small as a human hair—that deliver high-resolution imaging in regions inaccessible to conventional microscopes. Our patented technology enables new applications in research, advanced electronics failure analysis and intraoperative cancer detection.
Team:, Co-Founder, CEO; , CTO; , Principal Neuroscientist; Rafael Piestun, Co-Founder, President; , Co-Founder, Advisor; Co-Founder, Demetri Psaltis, Advisor
Affiliation: Թ of Colorado Boulder
Funding Round: Seed
Industry Applications: Cybersecurity, Hardware and Instrumentation, Medical Devices, Diagnostics
NemaLife is a TechBio company utilizing bio-intelligence to turn nutraceuticals into bioactive breakthroughs for human health and wellness. We combine whole-organism biology, microfluidic automation and AI to deliver fast, actionable, in vivo evidence for developing new consumer health ingredients and products.
Team:, Co-Founder, CEO; , Co-Founder, CTO; , Co-Founder, Head of Business Administration
Affiliation: Texas Tech Թ System
Funding Round: Series A
Industry Applications: Health and Wellness, Biotech
OsmoPure Technologies is a startup founded in 2024, focused on sustainable clean water solutions. Our pressure-driven distillation membrane technology efficiently delivers affordable, reliable, clean water globally, addressing water scarcity and fulfilling demanding industrial, municipal, and space mission requirements.
Team:, Co-Founder, CEO; , Co-Founder, CTO; , Co-Founder, CSO; , ECLSS Engineer; , Membrane Scientist
Affiliation: Թ of Colorado Boulder
Funding Round: Pre-Seed
Industry Applications: Aerospace, Advanced Materials, Environment and Sustainability, Cleantech
Perlion is a materials chemistry company developing next-generation sunscreen active ingredients. Its flagship product, Solir, is a first-of-its-kind sunscreen filter that blocks UV and high-energy visible light using only FDA-approved components.
Team:, Co-Founder, CEO; , Co-Founder, President; Alex Volosin, Co-Founder, CTO
Affiliation: Arizona State Թ
Funding Round: Seed
Industry Applications: Advanced Materials, Manufacturing, Chemicals
Rahm Sensor Development (“Rahm”) is building the Guardian™ platform, a multi-sensor, AI-driven, non-contact monitoring system delivering continuous physiological and safety awareness without wearables or wires. The platform is commercialized in corrections and expanding into elder care.
Team:, Co-Founder, CEO; , AI Director; , Software Director; , Operations;
Affiliation: Texas Tech Թ System
Funding Round: Seed
Industry Applications: Civic Engagement and Government, Hardware and Instrumentation, Sensors, Medical Devices, Diagnostics
Ramsi is an agentic AI for hotel pricing. Most hotels don’t have a formal pricing system, and the tools that exist are expensive, complex and require specialized staff. Ramsi delivers 24/7 dynamic pricing using a foundational pricing model that continuously learns and grows revenue.
Team:, Co-Founder; , Vice President of Revenue Strategy
Affiliation: Թ of Colorado Boulder
Funding Round: Seed
Industry Applications: Information Technology, Software, Tourism and Hospitality
SusMer is a Colorado-based healthcare biomaterials supplier that chemically manufactures poly-4-hydroxybutyrate (P4HB), a bioresorbable polymer for implantable medical devices. Our scalable process enables reliable supply, high purity and tunable properties for sutures, meshes and fibers.
Team:, President, CTO; , Scientific Advisor
Affiliation: Colorado State Թ
Funding Round: Seed
Industry Applications: Advanced Materials, Cleantech, Medical Devices, Biotech, Manufacturing, Chemicals
Vital Foams develops flowable, bioabsorbent foams for advanced wound care. Engineered for adaptability, our non-solidifying formulations enable field-ready delivery of hemostatic, anti-infective, wound healing and analgesic therapeutics in both civilian and military trauma settings.
Team: Kirk McGilvray, Co-Founder, CEO; Steve Dow, Co-Founder, CTO; Lynn Pezzanite, Co-Founder, CSO; Nicholas Alfonso, Co-Founder, CMO
Affiliation: Colorado State Թ
Funding Round: Seed
Industry Applications: Medical Devices, Biotech
X-Centric facilitates a more efficient, sustainable and resilient agricultural system driven by better soil measurement for people, planet and profit. We are replacing inefficient lab analysis with portable multimodal AI-enabled hardware, leveraging X-rays for instant geochemical insights spanning beyond carbon.
Team:, Co-Founder, CEO; Junghyun Lee, Co-Founder, Engineer; Matt Tighe, Advisor in Soil Science; David Weindorf, Advisor in Soil Science
Affiliation: Texas Tech Թ System
Funding Round: Seed
Industry Applications: Artificial Intelligence (AI) and Machine Learning, Environment and Sustainability, Cleantech, Financial Technology (Fintech), Food and Agriculture, Hardware and Instrumentation, Sensors, Information Technology, Software, Quantum
Avesta76 Therapeutics Inc.
Avesta76 is a revolutionary biotech company that is developing cancer medications that can treat over half of all cancers safely and effectively. To do that, we have found the key to bypassing p53 mutations and deletions. We will begin first in-human clinical trials in early 2026.
Team:, Co-Founder, CEO; Sanjay Awasthi, M.D., Co-Founder, Chief Research Officer; , Co-Founder, COO
Affiliation: Texas Tech Թ System
Industry Applications: Health and Wellness, Biotech, Artificial Intelligence (AI) and Machine Learning, Therapeutics
Cascade Biocatalysts Inc.
Cascade Bio empowers enzymes to change how molecules are made. Our product extends enzyme lifespans in chemical processes, lowering the cost of sustainable biomanufacturing. Over 20 companies have paid to try our product across pharmaceuticals, foods, recycling, specialty chemicals and biomining.
Team:, Co-Founder, CEO; (Alum: CU Boulder Chemical and Biological Engineering), Co-Founder, CSO
Affiliation: Թ of Colorado Boulder
Industry Applications: Advanced Materials,Artificial Intelligence (AI) and Machine Learning,Environment and Sustainability,Cleantech,Food and Agriculture,Biotech
Darwin Biosciences Inc.
Darwin Biosciences develops saliva-based diagnostics for early infection detection. Our technology identifies immune response signatures before symptoms escalate, enabling faster intervention. We aim to revolutionize infectious disease diagnostics, starting with sepsis.
Team: , CEO, Co-Founder; Sara Sawyer, Director, Co-Founder (CU Boulder BioFrontiers Institute)
Affiliation: Թ of Colorado Boulder
Industry Applications: Medical Devices, Biotech, Research and Exploration, Artificial Intelligence (AI) and Machine Learning
EerDx Inc.
EerDx uses earbud sleep diagnostics to transform how we diagnose and treat the 100 million Americans with sleep disorders. By delivering advanced clinical-grade sensors in a consumer earbud factor that a patient can easily use at home, EerDx is making home sleep testing cool!
Teams:, CEO, Co-Founder; , CTO, Co-Founder
Affiliation: Թ of Colorado Boulder
Industry Applications: Advanced Materials, Artificial Intelligence (AI) and Machine Learning, Sensors, Health and Wellness, Medical Devices, Diagnostics
Flow Aluminum Inc.
Flow Aluminum develops Aluminum-CO2 batteries for grid storage, microgrids and defense, offering extreme temperature performance (-40°C to 170°C), enhanced safety and CO2 utilization. Safer and cheaper than lithium-ion, our rechargeable system enables carbon removal and sustainable energy storage at scale.
Team: , Co-Founder, Chief Scientist; Co-Founder, CEO; , COO/CFO
Affiliation: Թ of New Mexico
Industry Applications: Aerospace, Advanced Materials, Civic Engagement and Government, Construction, Environment and Sustainability, Cleantech, Hardware and Instrumentation, Robotics, Sensors, Software, Manufacturing, Chemicals, Additive Manufacturing, Quantum, Research and Exploration, Social Enterprise, Smart Cities
Icarus Quantum Inc.
Quantum computers are yet to reach the size and scale required to unlock their true potential in exponential processing power. Icarus Quantum develops efficient and scalable quantum interconnects, providing scalability to quantum computers through modularity.
Team:, CEO, Founder; , Photonics Engineer; , Device Engineer; , , Advisor; , Advisor
Affiliation: Թ of Colorado Boulder
Industry Applications: Quantum
Illumen Therapeutics Inc.
Illumen Therapeutics is pursuing a p53 moonshot to transform cancer treatment by pioneering the development of PARN inhibitor drugs that increase functional p53, known as the 'Guardian of the Genome,' to treat aggressive cancers and improve patient survival.
Team: , CEO, Co-Founder; Roy Parker (CU Boulder BioFrontiers Institute), Co-Founder, Advisor; , CFO; , Interim CSO
Affiliation: Թ of Colorado Boulder
Industry Applications: Health and Wellness, Therapeutics, Biotech, Artificial intelligence (AI) and Machine Learning
Latimer Controls Inc.
Latimer Controls provides a software solution that addresses the critical issue of solar power intermittency, enabling precise real-time control and optimization of solar output. This transforms standalone solar generation into a controllable, dispatchable and flexible resource for the power grid.
Team: (, Alum: CU Boulder Applied Mathematics) CEO, Co-Founder; (Alum: CU Boulder Ann and H.J. Smead Aerospace Engineering Sciences), Co-Founder; (Alum: CU Boulder Chemical and Biological Engineering), Co-Founder.
Affiliation: Թ of Colorado Boulder
Industry Applications: Artificial Intelligence (AI) and Machine Learning, Environment and Sustainability, Cleantech, Software, Smart Cities
Mana Battery Inc.
Founded by experienced battery technologists and entrepreneurs, Mana Battery delivers on the promise of the sodium-ion battery with best-in-class cost and performance through a proprietary low-cost, fire-extinguishing electrolyte platform and a high-energy battery cell design that offers higher energy density than LFP Li-ion at half-the-cost.
Team: , Co-Founder, CEO; , Co-Founder, CTO; (CU Boulder Paul M. Rady Mechanical Engineering), Co-Founder, Chief Scientific Advisor; , Member of the Board of Directors; , Director of Materials Engineering and R&D; , Senior Cell Engineer; , Associate Cell Engineer; , Senior Business Advisor
Affiliation: Թ of Colorado Boulder
Industry Applications: Advanced Materials, Cleantech, Manufacturing
OMC Thermochemistry
OMC Thermochemistry offers a low-cost, massively scalable route for the efficient, highly durable production of hydrogen or the transformation of CO2 back into useful fuels and chemicals using heat, a novel active material, and globally abundant resources within existing industrial formats and competencies.
Team: (CU Boulder Chemical and Biological Engineering), Co-Founder, CSO; , Co-Founder, CEO; , Senior Process Engineer
Affiliation: Թ of Colorado Boulder
Industry Applications: Aerospace, Advanced Materials, Environment and Sustainability, Cleantech, Chemicals
Otoro Energy Inc.
Otoro Energy is revolutionizing long-duration energy storage with a high-efficiency, low-cost flow battery. Backed by the largest U.S. utility and over $6 million in DOE grants, our non-flammable, non-toxic technology enables safe, 10+ hour discharge, delivering reliable, scalable and cost-effective grid resilience.
Team: (frm. CU Boulder Chemistry, RASEI)
Affiliation: Թ of Colorado Boulder
Industry Applications: Cleantech, Hardware and Instrumentation
PAGE Technologies Inc.
PAGE Technologies is redefining agricultural and environmental monitoring with a breakthrough analytics platform. Our proprietary printed electronics deliver real-time, ultra-low-cost data collection. With seamless API integration, PAGE enables strategic partners to scale impact and unlock new revenue opportunities.
Team: (CU Boulder College of Engineering and Applied Science), Co-Founder, CEO; , Co-Founder, CTO; Cameron Handeland, Lead Systems Engineer
Affiliation: Թ of Colorado Boulder
Industry Applications: Advanced Materials,Artificial Intelligence (AI) and Machine Learning, Environment and Sustainability,Cleantech, Food and Agriculture, Sensors
Paramium Technologies Inc.
Paramium is an aerospace telecom company focused on building a global network of advanced ground stations for multiband satellite connectivity. Its centralized system simplifies scheduling, connection, downloading and mission control, much like scheduling an online conference.
Team:, CEO, Co-Founder; , CTO, Co-Founder; (), COO, , CFO
Affiliation: Թ of Arizona
Industry Applications: Aerospace
TheraCea Pharma LC
TheraCea Pharma is a biotechnology company dedicated to developing a new generation of radiopharmaceutical compounds as theranostics, molecules that have both diagnostic and therapeutic applications, and advanced diagnostics for detecting and treating cancers and neurological disorders.
Team: , CEO, Co-Founder; , Vice President of R&D; , Fractional CFO; , Chief Business Officer; , Regulatory Affairs Consultant; , Manager of R&D; , Manager of Business Operations; , Scientist II; , Business Intelligence Officer
Affiliation: Թ of Arizona
Industry Applications: Therapeutics, Diagnostics, Biotech
Tynt Technologies Inc.
ղԳ’s platform technology enables real-time dynamic tinting through reversible metal electrodeposition (RME). It’s tunable by application, integrates into glass or plastic, has a wide dynamic range, neutral color, low cost and is flexible, unlocking new possibilities for smart materials.
Team: , CEO; , COO; , CTO; , Chief Scientist
Affiliation: Թ of Colorado Boulder
Industry Applications: Advanced Materials, Augmented Reality (AR) and Virtual Reality (VR), Environment and Sustainability, Cleantech, Smart Cities
Batteries Beyond Batteries Corp.—Developing a patented vehicle immobilizer to provide vehicles with improved and convenient protection against thefts, with the potential of replacing existing car keys or key fobs. Affiliation: Թ of Colorado Denver
BioSensor Solutions—Provides an organic sensor technology that measures and validates soil health critical for fresh food safety, agriculture production and climate sustainability. Affiliation: Թ of Colorado Boulder
Blue Cubed LLC—Developing optical communication systems for the rapidly growing small satellite market. Affiliation: Թ of Colorado Boulder
Colorado Earth LLC—Designs, manufactures and builds using locally-produced masonry blocks. Affiliation: National Renewable Energy Laboratory (NREL)
D3Sciences Inc.—Empowering tissue-based diagnostics for personalized care. Affiliation: Թ of Arizona
Ezalife LLC—Develops simple, safe securement methods for a wide variety of surgically placed tubing to improve clinical outcomes and patient quality of life. Affiliation: Թ of Colorado Anschutz Medical Campus
Green Steel Environmental LLC—Improves water and air quality by making sustainable improvements to wastewater and biogas treatment. Affiliation: Թ of Colorado Boulder
Mach Electric—A Boulder R&D group developing sustainable aviation and materials technologies with a core product that aims to produce aerospace-grade carbon fiber through a process that directly sequesters carbon dioxide. Affiliation: Թ of Colorado Boulder
Metfora—Metfora’s novel AI-enabled diagnostic test overcomes the difficulty of detecting chronic diseases by discerning disease-specific changes in the levels of metabolites circulating in the blood, enabling doctors to find and begin treating these diseases in their early, more treatable stages. Affiliation: Թ of Arizona
Neurofluidic Diagnostics—Offers advanced data-mapping services for neurodegenerative biomarkers using proprietary neurofluidics, facilitating precise disease progression modeling and enhancing early diagnostics to support drug development efforts. Affiliation: Montana State Թ
New Day Hydrogen Inc.—Making hydrogen fueling economical for fleets of heavy-duty electric vehicles as they take their first, incremental steps towards zero emissions; with the proprietary HubStarter system, they show fleets transitioning as few as five trucks the path to beating diesel in applications where batteries just don’t fit. Affiliation: Colorado State Թ
NitroCat Energies—Developing modular and electrified systems powered by renewable electricity to convert nitrogen feedstock in the agricultural waste stream (run-off) to high-value and high-energy fuels and chemicals (ammonia, urea) without the high heat and pressure traditionally used in the industry. Affiliation: Colorado State Թ
Pando Strategies/Click!—A hands-free computer interface that allows users to interact with machines through a comfortable wearable device, analogous to using a finger to type on a keypad where the tongue substitutes for the finger and the teeth for the keypad. Affiliation: Թ of Colorado Boulder
Pearl Scientific—A translational breast cancer research program to translate novel therapies for patients with recurrent/refractory/metastatic disease with a focus on patients younger than 45. Affiliation: Թ of Colorado Anschutz Medical Campus
PrecisionTerra—Improves GPS receivers’ signal tracking capabilities and positional accuracy in challenging environments such as dense cities, with a vision to improve high-definition map-based positioning and navigation systems for autonomous vehicles in such environments. Affiliation: Թ of Colorado Boulder
Reglagene Inc.—A therapeutics company that leverages its expertise in the design and development of brain penetrant medicines to create breakthrough therapies for the safe and effective treatment of brain diseases. Affiliation: Թ of Arizona
RockyTech—Develops compatibilizers that enhance the quality of post-consumer and post-industrial recycled polypropylene (PP) and polyethylene (PE) waste blends for reuse in molding applications (3D printing, packaging, cosmetics). Affiliation: Թ of Colorado Boulder
Seedling Biosystems—Bioengineering soybeans for the sustainable production of essential chemistries for manufacturing, therapeutics and food. Affiliation: Թ of Colorado Boulder
SusMer Inc.—Creatively disrupting the manufacturing process with a one-step chemical process of a medical-grade material, called P4HB, where the only other manufacturer has a microbial process and was acquired by Becton Dickinson for around $750 million in 2021 Affiliation: Colorado State Թ
SuviCa Inc.—An oncology drug discovery and development company to create therapeutic opportunities for hard-to-treat cancers, leveraging deep knowledge of tumor growth and regeneration into proprietary screening platforms and identifying novel oncology agents that they de-risk through robust preclinical and clinical studies before out-licensing. Affiliation: Թ of Colorado Boulder
TheraVac Biologics—Developing vaccines and immunotherapies for diseases that are caused by misfolded protein aggregates and/or aberrant inflammation that provide a cheaper, safer and more convenient approach to treat chronic diseases, in particular neurodegenerative conditions such as Alzheimer’s disease. Affiliation: Թ of New Mexico
VitaWave Tech Inc.—Transforming healthcare with an innovative eBP device, a cuffless, ear canal-based blood pressure monitor that enables seamless, non-intrusive monitoring for patients and healthcare providers, redefining how to manage blood pressure, enhance lives and improve outcomes. Affiliation: Թ of Colorado Boulder
WHISPER Energy—A ‘low-powered’ (no batteries or power outlet required) wireless sensor platform using radio frequency identification (RFID) to power the system and securely detect human occupancy and air quality levels within homes or commercial buildings, thus reducing power consumption by 30% or more. Affiliation: Թ of Colorado Boulder
Afference Inc.—Afference powers the feeling of touch in the digital world. Affiliation: Թ of Colorado Boulder.
Aqualung Therapeutics Corp.—Aqualung Therapeutics Corp. is an immunotherapy company focused on developing therapeutics for diseases of unchecked inflammation and fibrosis. Affiliation: Թ of Arizona.
Aspero Medical Inc.—Aspero Medical is enabling intraluminal endoscopic surgery through novel devices that improve access, stability, traction, and precision instrument manipulation as part of the shift toward less invasive procedures, from laparoscopic to intraluminal surgery. Affiliation: Թ of Colorado Boulder.
Beryl Therapeutics Inc.—Beryl is an early-stage drug development company poised to revolutionize the bone market with an anticipated safety profile that will disrupt the osteoporosis market and unlock the pediatric bone market. Affiliation: Թ of Colorado Anschutz Medical Campus.
Blaze Energy Technologies LLC—Blaze Energy is developing catalytic reforming technology for the efficient production of H2/NH3 fuels, which serve as carbon-free, drop-in replacements for hydrocarbons in combustion applications. Affiliation: Colorado School of Mines.
CarbeniumTec LLC—CarbeniumTec LLC is developing a metal-free, all-organic battery for long-duration energy storage, providing a solution to the growing need for electricity storage without the environmental impacts of conventional batteries. Affiliation: Թ of Arizona.
Cardiost—Cardiost’s mission is to improve the quality of life for patients suffering from Heart Failure with preserved Ejection Fraction (HFpEF) by developing a fully implantable heart assist pump for late-stage HFpEF. Affiliation: Թ of Denver.
Cascade Biocatalysts—Cascade Biocatalysts makes enzymes rugged and reliable for widespread adoption in chemical manufacturing, reducing the cost and environmental impact of diverse manufacturing processes. Affiliation: Թ of Colorado Boulder.
Chiima Therapeutics—Chiima Therapeutics is a preclinical biotech company investigating a non-hormonal treatment for moderate to severe endometriosis-related pain in adult women. Affiliation: Թ of New Mexico.
Codelucida Inc.—Codelucida provides disruptive error-correction solutions supporting the next generation of NAND flash memory chips, improving error correction and scalability while reducing power usage. Affiliation: Թ of Arizona.
Curable Composites—Curable Composites produces revolutionary materials, including 3D printing carbon fiber in mid-air and breakthroughs in foam manufacturing, leveraging over a decade of research. Affiliation: Colorado State Թ.
GelSana Therapeutics Inc.—GelSana is a hydrogel wound dressing company offering products that improve wound healing by reducing inflammation and providing sustained drug delivery. Affiliation: Colorado School of Mines.
LumenAstra—LumenAstra is commercializing a wearable, non-invasive sensor that measures core body temperature several centimeters below the skin, with applications in cardiac surgery, stroke recovery, chemotherapy, and consumer thermometers. Affiliation: Թ of Colorado Boulder.
Prometheus Materials Inc.—Prometheus Materials develops, manufactures, and licenses the use of microalgae to reduce and eliminate CO2 from concrete building materials. Affiliation: Թ of Colorado Boulder.
Radanta Corporation—Radanta Corporation is developing innovative energy harvesting technology. Affiliation: Թ of Colorado Boulder.
RaeSedo, Inc.—RaeSedo, a spin-out from the Թ of Arizona, is developing novel therapeutics for asthma based on an understanding of lung pathology. Affiliation: Թ of Arizona.
Reglagene Inc.—Reglagene is a preclinical-stage therapeutics company developing breakthrough therapy for the treatment of brain cancers. Affiliation: Թ of Arizona.
Sentinel Fertigation—Sentinel Fertigation provides image-based crop monitoring and nitrogen management solutions that improve farm profitability and preserve the environment by aligning nitrogen applications with crop needs. Affiliation: Թ of Nebraska - Lincoln.
TissueForm—TissueForm harnesses the natural, restorative power of tissue extracellular matrix to fill volumetric defects, integrating with host tissue and promoting healing. Affiliation: Թ of Colorado Boulder.
Tynt Technologies Inc.—Tynt Technologies is commercializing the next generation of dynamic windows to improve the comfort and energy efficiency of homes. Affiliation: Թ of Colorado Boulder.
uPetsia Inc.—uPetsia solves bad dog breath with a canine oral bacteria modified to produce mint aromas for hours, used as a feed ingredient. Affiliation: Թ of Arizona.
Aspero Medical, Inc.—Focuses on improving gastrointestinal endoscopy with enhanced device performance to improve patient outcomes, all while saving time and money. Affiliation: CU Boulder.
Aurora Oncology, Inc.—Develops novel therapies for bladder cancer. Affiliation: CU Anschutz.
Beyond Copper—Makes safe copper surfaces and powders for coatings and filters that are nearly instantly antimicrobial, unlike traditional copper. Affiliation: Colorado School of Mines.
Blue Cubed, LLC—Builds optical and radio frequency communication terminals for the growing small satellite market. Affiliation: CU Boulder.
Botanisol Analytics—Developing the world’s first autonomous disease detector for national security efforts. Affiliation: Թ of Arizona.
Ensign Pharmaceutical, Inc.—Develops and markets novel pharmaceutical products to free patients with musculoskeletal disorders and inflammatory diseases from pain and disability without harmful side effects. Affiliation: Թ of Nebraska Medical Center.
EvoEndo, Inc.—Developed a single-use system for diagnostic upper endoscopies to be performed without the use of general anesthesia or sedation. Affiliation: CU Anschutz.
Global Laparoscopy Solutions—Created a portfolio of low-cost, portable laparoscopy devices for minimally invasive surgeries. Affiliation: Թ of Nebraska Medical Center.
HiveTech Solutions—Commercializing its proprietary climate-smart technology to improve honeybee survival. Affiliation: CU Boulder.
LumenAstra—Commercializing a wearable, non-invasive core body temperature sensor for clinical, consumer, military, and athletic applications. Affiliation: CU Boulder.
Mallinda, Inc.—Solving the problem of structural composite waste by enabling end-of-life circularity of composite parts. Affiliation: CU Boulder.
Mars Materials—Developing a new pathway for carbon fiber and acrylamide production using CO₂ and bio-based inputs as raw materials. Affiliation: National Renewable Energy Laboratory (NREL).
Modendo Inc.—Adapts and optimizes systems to create a robust, flexible, and compact prototype of an ultrathin endoscope for use in neuroscience labs. Affiliation: CU Boulder.
Nano Magnetic Solutions—Developed a brain simulation toolbox for in vitro research for neurological disease treatments. Affiliation: Montana State Թ.
New Day Hydrogen, LLC—Builds, markets, and develops projects around green hydrogen, focusing on fleet fueling and longer-lead opportunities in communities and utilities. Affiliation: Colorado State Թ.
OMC Hydrogen—Creates renewable hydrogen to decarbonize fuels and chemicals using a thermochemical process with significant cost advantages over electrolysis. Affiliation: CU Boulder.
OTORO Energy—Manufactures megawatt-scale energy storage systems to support the electric grid and infrastructure with safe, patented battery materials. Affiliation: CU Boulder.
Polaris Electro-Optics, Inc.—Provides ferroelectric nematic liquid crystals and device reference designs for CMOS foundries to enhance electro-optic modulators. Affiliation: CU Boulder.
Reglagene—Pioneers safe and effective precision chemotherapy medicines that selectively kill cancer cells without the toxic side effects of existing agents. Affiliation: Թ of Arizona.
RespirAI Medical—Developed wearable technology that tracks the progression of COPD and can predict incoming disease exacerbations. Affiliation: Թ of Nebraska Medical Center.
Respirogen, Inc.—Technology delivers oxygen to the bloodstream independent of the lungs to reduce systemic hypoxia for lung disease patients. Affiliation: CU Boulder.
SaiOx, Inc.—Created Hespiro, a patented respiratory assistance device that utilizes the proven benefits of heliox in a closed-loop system for people suffering from COPD. Affiliation: Թ of Arizona.
SARUS Lifting—A software tool to help crane and construction companies reduce time spent developing lift plans while improving their quality for better job site safety. Affiliation: CU Boulder.
Scintillation Nanotechnologies—Developed novel nanoparticles to detect continuous radioisotopes in non-toxic, aqueous environments, including inside living cells and tissues. Affiliation: Թ of Arizona.
TheraCea Pharma—Developing new diagnostic agents to assess early responses in immunotherapy through PET imaging. Affiliation: Թ of Arizona.
Think Bioscience—A new platform combining applied microbiology, enzymology, and data science to develop small-molecule therapeutics guided by living systems for better medicines. Affiliation: CU Boulder.
Tynt Technologies—Offers dynamic windows based on reversible metal deposition technology to control light and heat flow with 100% blackout/privacy. Affiliation: CU Boulder.
Vitro3D—Reimagining drug discovery research through mechanically enhanced and geometrically accurate 3D printed tissue for preclinical testing. Affiliation: CU Boulder.
Xoralgo, Inc.—Built the next generation of patented computer storage technology that prevents data loss and dramatically reduces the cost of storing data. Affiliation: Թ of Arizona.
Alpenglow Instruments—Alpenglow Instruments designs, builds, and supports high-quality instrumentation used to study clouds, aerosols, and the Earth's atmosphere. Affiliation: Թ of Wyoming.
Arpeggio Bio—Arpeggio Bio uses machine learning and RNA to make drugs against previously undruggable targets in cancer and inflammatory diseases. Affiliation: Թ of Colorado Boulder.
Aspero Medical, Inc.—Aspero Medical focuses on improving gastrointestinal endoscopy for the patient and physician. Their technology enhances device performance, saving time and money, while improving patient outcomes. Affiliation: Թ of Colorado Boulder.
BCell Solutions, Inc.—BCell Solutions is a pre-clinical biopharmaceutical company commercializing immunotherapies that harness immune cell-surface signaling to stop inflammation. Affiliation: Թ of Colorado Colorado Springs.
BromeCare Therapeutics, LLC—BromeCare Therapeutics is rapidly developing a plant-derived therapeutic to disrupt SARS-CoV-2 spike proteins and prevent COVID-19 infection. Affiliation: Թ of Nebraska Medical Center.
CellDrop Biosciences, Inc.—CellDrop is commercializing a stem cell therapy developed to quickly and permanently heal musculoskeletal injuries in racehorses. Affiliation: Թ of Wyoming.
Double Helix Optics—Double Helix Optics designs and manufactures sensors and imaging modules for precision 3D imaging used in life and material sciences, industrial inspection, and machine vision. Affiliation: Թ of Colorado Boulder.
EvoEndo, Inc.—EvoEndo builds innovative pediatric endoscopy systems that allow diagnostic upper endoscopies to be performed comfortably and quickly without the need for general anesthesia. Affiliation: Թ of Colorado Anschutz Medical Campus.
GPER G-1 Development Group—GPER G-1 Development Group is developing a novel therapeutic for the treatment of diabetes and obesity. Affiliation: Թ of New Mexico.
Inherent Biosciences, Inc.—Inherent Biosciences is a molecular diagnostics company at the intersection of epigenetics and artificial intelligence, tackling clinical problems such as infertility, autoimmune diseases, and COVID-19 disease severity. Affiliation: Թ of Utah.
Laporte Immunotherapeutics—Laporte Immunotherapeutics is developing transformative immune-based therapies for upper respiratory and eye infections using immune-stimulatory nanoparticles. Affiliation: Colorado State Թ.
Big Blue Technologies—Makes magnesium metal using a novel process technology that consumes 60 percent less energy than the dominant incumbent process, resulting in a 50 percent reduction in cost of goods sold compared to the monopolistic U.S. producer. Affiliation: CU Boulder.
BioLoomics, Inc.—Provides a B2B service to pharma R&D companies that predicts clinically relevant effects of drugs using a high-throughput platform drug screening technology. Affiliation: CU Boulder.
Cetya Therapeutics—Developing HDAC inhibitors, analogs of largazole, a natural product Class I-restricted HDAC inhibitor, focused on solid tumors in oncology and hemoglobinopathies like sickle cell disease. Affiliation: Colorado State Թ.
Earable, Inc.—The world’s first and most advanced in-ear health improvement platform for sleep and health monitoring applications, revolutionizing cognitive healthcare with smart earphones. Affiliation: CU Boulder.
Emergy Foods—A whole muscle, plant-based meat alternative company that developed a sustainable, proprietary process to produce food ingredients and finished goods from fungal mycelium. Affiliation: CU Boulder.
Ezalife, LLC—Designs and develops medical devices that make life easier for individuals with complex medical needs. Its first product, the Button Huggie, is a precision-designed gastrostomy button securement device. Affiliation: CU Anschutz.
GenoFab, Inc.—Developing a software tool-chain to write and read self-documenting DNA molecules. Affiliation: Colorado State Թ.
Lab79 Technologies, Inc.—Developing a method to sequence DNA by monitoring changes in force as single-stranded DNA is pulled through an interface. Affiliation: N/A.
Microbial Pulse Diagnostics—Enabling point-of-care, data-driven antibiotic prescriptions by providing physicians with a list of effective drugs in under two hours. Affiliation: National Institute of Standards and Technology (NIST).
New Iridium, LLC—Produces organic photo redox catalysts (PCs) for light-driven chemical reactions that accelerate pharma drug development and reduce drug manufacturing costs. Affiliation: Colorado State Թ, CU Boulder.
OptiEnz Sensors—An instrumentation system that incorporates biosensors for continuous monitoring of organic chemical concentrations in water and aqueous solutions. Affiliation: Colorado State Թ.
PhotonPharma—An immune oncology company developing a breakthrough technology to stimulate a patient’s immune system to seek out and destroy their cancer cells. Affiliation: Colorado State Թ.
SiVEC Biotechnologies—A delivery platform for nucleic acid drugs and gene-editing tools using non-pathogenic bacteria for stable and specific delivery to mucosal tissues without host genomic integration. Affiliation: Colorado State Թ.
Starfire Energy—Develops systems to produce carbon-free ammonia from air and water using clean electricity, leveraging a patent-pending catalyst and novel removal method. Affiliation: Colorado School of Mines.
Strivision—Developing new condition-oriented pulmonary diagnostic tools aimed at early diagnosis of chronic respiratory conditions through infrared CO2 imaging and AI-driven analysis. Affiliation: CU Denver.
TissueForm—A microparticle tissue technology that targets scarring, wrinkles, and tissue loss due to aging or injury. Affiliation: CU Boulder.
VetMeasure—Produces MeasureON!, a canine harness that enables accurate detection of an animal’s health statistics to optimize care and treatment options. Affiliation: Colorado State Թ.
VitriVax—A platform technology enabling the preparation of thermostable, single-shot vaccines. Affiliation: CU Boulder.
Access Sensor Technologies—Develops inexpensive and accurate environmental and biological tests. Affiliation: Colorado State Թ
AmideBio—Developing glucose-responsive insulins (GRIs), a treatment paradigm that can redefine how diabetes is treated. Affiliation: CU Boulder.
Arpeggio Biosciences—Generates novel insights about a compound’s biological mechanism of action, significantly reducing the risk of clinical failure and associated expense. Affiliation: CU Boulder.
Aspero Medical—Uses micro-texturing to create medical balloons with improved anchoring during in vivo use. Affiliation: CU Boulder.
ASTRALiTe, Inc.—Creates a real-time, drone-mounted LiDAR system capable of measuring underwater objects and topography with unprecedented cm-level resolution. Affiliation: CU Boulder.
BCell Solutions—Develops novel immunotherapies to treat autoimmune diseases, cancers, and neurodegenerative diseases. Affiliation: UCCS.
Colorado Research Partners—Develops novel drugs to block the effects of sugar and alcohol, addressing sugar cravings, obesity, hypertension, diabetes, and liver disease. Affiliation: CU Anschutz.
DreamFace Technologies—Creates "Ryan," a social companion robot for dementia patients that delays the onset of advanced dementia through stimulating games, music, and crafts. Affiliation: Թ of Denver.
Katharos, Inc.—Develops a medical device used during hemodialysis to remove phosphates that contribute to cardiovascular disease and death. Affiliation: CU Anschutz.
Kelvin Thermal Technologies, Inc.—Develops the thinnest and lightest cooling solutions for smartphones, AR/VR devices, and future vehicles. Affiliation: CU Boulder.
MRX Analytics—Creates a new way of measuring temperature in Magnetic Resonance Imaging (MRI). Affiliation: UCCS.
MyRoomSolution d.b.a. 99Agree—Helps people learn to live, share, and get along with their roommates. Affiliation: CU Boulder.
New Iridium—Produces organic photoredox catalysts (PCs) for light-driven chemical reactions. Affiliation: Colorado State Թ
OptiEnz Sensors—Provides an instrumentation system incorporating biosensors for continuous monitoring of organic chemical concentrations in water and aqueous solutions. Affiliation: Colorado State Թ and CU Boulder
PhotonPharma, Inc.—Develops cancer vaccines applicable to all cancers, using live inactivated tumor cells with full preservation of neo-antigens and cell structure. Affiliation: Colorado State Թ
Prieto Battery, Inc.—Commercializes patented 3D solid-state lithium-ion battery technology to accelerate innovation in energy storage. Affiliation: Colorado State Թ
Respirogen—Develops oxygen microbubble (OMB) technology to provide oxygen in lung-compromised patients, maintaining tissue viability while injuries heal. Affiliation: CU Boulder.
RxRevu—Provides real-time, patient-specific cost and drug options aligned with formulary and benefit data for prescribers at the point of care. Affiliation: CU Anschutz.
SummitDX—Develops a saliva-based molecular test for head and neck cancer. Affiliation: CU Anschutz.
SuviCa—Focuses on cancer drug discovery and development targeting protein homeostasis. Affiliation: CU Boulder.
ThromboTherapeutics, Inc.—Develops coagulation management tools, such as the tPA-Challenge Assay, to detect patients at high risk for bleeding in trauma environments. Affiliation: CU Anschutz.
Tissue Fusion—Surgically fuses tissues using laser energy instead of sutures or staples. Affiliation: UCCS.
Triple Endoscopy, Inc.—Creates a modified multi-use nasal endoscope for pediatric and adult patients. Affiliation: CU Anschutz.
VetMeasure—Produces harnesses to detect an animal’s health statistics for optimized care and treatment. Affiliation: Colorado State Թ
VitriVax—Develops a platform technology enabling thermostable, single-shot vaccines. Affiliation: CU Boulder.
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